R&B icon Tina Turner has survived a lot of horrors during her 79 years — including terrifying abuse by ex-hubby Ike Turner — but medical experts fear she’s facing her final curtain call as her lifesaving kidney transplant lurches from crisis to crisis!

Gasps were heard as the Proud Mary songbird arrived looking shockingly unrecognizable with a “moon face” at the Broadway opening of Tina: The Tina Turner Musical on Nov. 7.

New York internist Dr. Stuart Fischer, who hasn't treated the star, says the appearance of the What’s Love Got to Do with It singer is “a sign that she’s taking powerful immunosuppressant drugs to keep her body from rejecting the organ” her husband Erwin Bach donated to save her life in 2016.

“It can also be a sign that her body is rejecting the organ,” notes the author of Dr. Fischer’s Little Book of Big Medical Emergencies.

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